(607) 238-2789 info@freshysites.com

Synthes Spine Company | Cleanroom Expansion

Cleanroom Expansion
Musculoskeletal Transplant Foundation

Jessup, PA


Synthes Spine Company
Paoli, PA

Design Professional

Integrated Project Services
Lafayette Hill, PA



Installation of a Class 10 cleanroom expanded this manufacturing facility’s capacity. Because of the owner’s precise production requirements, the cleanroom space utilized strict environmental controls to regulate temperature and minimize air contamination. The tie-ins to existing cleanrooms on this project required L.R. Costanzo to adhere to strict timelines since much of the work was performed during MTF’s shutdowns or adjacent to active production areas.


  • Adjacent to active production areas
  • ISO standards for piping – strict certification & welding documentation


  • Isolation plans and engineering controls
  • Process piping to prepare for tie-ins accomplished during shutdowns


L.R. Costanzo experts also procured, supervised and installed:

  • HEPA filtration to provide 99.9995% pure air
  • Process piping
  • Tie-ins to existing cleanrooms